Diminished neurogenic femoral artery vasoconstrictor response in a Zucker obese rat model: differential regulation of NOS and COX derivatives.

Diminished neurogenic femoral artery vasoconstrictor response in a Zucker obese rat model: differential regulation of NOS and COX derivatives.

OBJECTIVE: Peripheral arterial disease is one of the macrovascular complications of type 2 diabetes mellitus. This study addresses femoral artery regulation in a prediabetic model of obese Zucker rats (OZR) by examining cross-talk between endothelial and neural factors. METHODS AND RESULTS: Arterial...

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Bibliographic Details
Main Authors: Ana Cristina Martínez, Medardo Hernández, Susana Novella, María Pilar Martínez, Rosa María Pagán, Carlos Hermenegildo, Albino García-Sacristán, Dolores Prieto, Sara Benedito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4162543?pdf=render

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http://europepmc.org/articles/PMC4162543?pdf=render

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