Single‐Cell RNA‐Seq of T Cells in B‐ALL Patients Reveals an Exhausted Subset with Remarkable Heterogeneity

Abstract Characterization of functional T cell clusters is key to developing strategies for immunotherapy and predicting clinical responses in leukemia. Here, single‐cell RNA sequencing is performed with T cells sorted from the peripheral blood of healthy individuals and patients with B cell‐acute l...

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Bibliographic Details
Main Authors: Xiaofang Wang, Yanjuan Chen, Zongcheng Li, Bingyan Huang, Ling Xu, Jing Lai, Yuhong Lu, Xianfeng Zha, Bing Liu, Yu Lan, Yangqiu Li
Format: Article
Language:English
Published: Wiley 2021-10-01
Series:Advanced Science
Subjects:
Online Access:https://doi.org/10.1002/advs.202101447