Metastatic colorectal cancer and severe hypocalcemia following irinotecan administration in a patient with X-linked agammaglobulinemia: a case report

Metastatic colorectal cancer and severe hypocalcemia following irinotecan administration in a patient with X-linked agammaglobulinemia: a case report

Abstract Background X-linked agammaglobulinemia (XLA) is a primary immunodeficiency disorder caused by germline mutations in the Bruton tyrosine kinase (BTK) gene on X chromosome. These mutations disturb B-cell development, decrease immunoglobulin levels, increase susceptibility to infection or neop...

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Bibliographic Details
Main Authors: Mingming Li, Wei Chen, Xiaomeng Sun, Zhipeng Wang, Xun Zou, Hua Wei, Zhan Wang, Wansheng Chen
Format: Article
Language:English
Published: BMC 2019-09-01
Series:BMC Medical Genetics
Subjects:
X-linked agammaglobulinemia
Hypocalcemia
Whole exome sequencing
Therapeutic drug monitoring
And irinotecan
Online Access:http://link.springer.com/article/10.1186/s12881-019-0880-1

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http://link.springer.com/article/10.1186/s12881-019-0880-1

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