Delayed Rifampin Administration in the Antibiotic Treatment of Periprosthetic Joint Infections Significantly Reduces the Emergence of Rifampin Resistance

Delayed Rifampin Administration in the Antibiotic Treatment of Periprosthetic Joint Infections Significantly Reduces the Emergence of Rifampin Resistance

Rifampin is one of the most important biofilm-active antibiotics in the treatment of periprosthetic joint infection (PJI), and antibiotic regimens not involving rifampin were shown to have higher failure rates. Therefore, an emerging rifampin resistance can have a devastating effect on the outcome o...

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Bibliographic Details
Main Authors: Ali Darwich, Franz-Joseph Dally, Mohamad Bdeir, Katharina Kehr, Thomas Miethke, Svetlana Hetjens, Sascha Gravius, Elio Assaf, Elisabeth Mohs
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antibiotics
Subjects:
rifampin
resistance
periprosthetic joint infection
PJI
antibiotic
outcome
Online Access:https://www.mdpi.com/2079-6382/10/9/1139

Internet

https://www.mdpi.com/2079-6382/10/9/1139

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