Monoketone analogs of curcumin, a new class of Fanconi anemia pathway inhibitors

<p>Abstract</p> <p>Background</p> <p>The Fanconi anemia (FA) pathway is a multigene DNA damage response network implicated in the repair of DNA lesions that arise during replication or after exogenous DNA damage. The FA pathway displays synthetic lethal relationship wit...

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Bibliographic Details
Main Authors: Turker Mitchell S, Sun Aiming, Yang Chao, McCarroll Matthew, Hiddingh Sanne, Landais Igor, Snyder James P, Hoatlin Maureen E
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/8/1/133