The lncRNA CCAT1 upregulates TGFβR1 via sponging miR-490-3p to promote TGFβ1-induced EMT of ovarian cancer cells

Abstract Background Ovarian cancer is the fifth leading cause of cancer deaths in women worldwide. LncRNACCAT1 was reported to play a critical role in cell metastasis of ovarian cancer. However, little is known about the detailed mechanism of how CCAT1 enhances TGFβ1-induced EMT of ovarian cancer ce...

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Bibliographic Details
Main Authors: Yang Mu, Na Li, Yu-Lan Cui
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Cancer Cell International
Subjects:
EMT
Online Access:http://link.springer.com/article/10.1186/s12935-018-0604-1