N-glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function

N-glycosylation as a Tool to Study Antithrombin Secretion, Conformation, and Function

N-linked glycosylation is a crucial post-translational modification involved in protein folding, function, and clearance. N-linked glycosylation is also used therapeutically to enhance the half-lives of many proteins. Antithrombin, a serpin with four potential N-glycosylation sites, plays a pivotal...

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Bibliographic Details
Main Authors: Sonia Águila, Rosina Noto, Ginés Luengo-Gil, Salvador Espín, Nataliya Bohdan, María Eugenia de la Morena-Barrio, Julia Peñas, Maria Carmen Rodenas, Vicente Vicente, Javier Corral, Mauro Manno, Irene Martínez-Martínez
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:International Journal of Molecular Sciences
Subjects:
Glycosylation
folding
antithrombin
serpin
coagulation
thrombosis
Online Access:https://www.mdpi.com/1422-0067/22/2/516

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https://www.mdpi.com/1422-0067/22/2/516

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