In vivo evidence of D3 dopamine receptor sensitization in parkinsonian primates and rodents with l-DOPA-induced dyskinesias

In vivo evidence of D3 dopamine receptor sensitization in parkinsonian primates and rodents with l-DOPA-induced dyskinesias

A growing body of evidence indicates a role for D3 receptors in l-DOPA-induced dyskinesias. This involvement could be amenable to non-invasive in vivo analysis using functional neuroimaging. With this goal, we examined the hemodynamic response to the dopamine D3-preferring agonist 7-hydroxy-N,N-di-n...

Full description

Bibliographic Details
Main Authors: Rosario Sánchez-Pernaute, Bruce G. Jenkins, Ji-Kyung Choi, Yin-Ching Iris Chen, Ole Isacson
Format: Article
Language:English
Published: Elsevier 2007-08-01
Series:Neurobiology of Disease
Subjects:
Dyskinesia
Parkinson’s disease
Dopamine
Dopamine receptor
D3
Striatum
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996107000927

Internet

http://www.sciencedirect.com/science/article/pii/S0969996107000927

Similar Items