P-glycoprotein (ABCB1) and Oxidative Stress: Focus on Alzheimer’s Disease

ATP-binding cassette (ABC) transporters, in particular P-glycoprotein (encoded by ABCB1), are important and selective elements of the blood-brain barrier (BBB), and they actively contribute to brain homeostasis. Changes in ABCB1 expression and/or function at the BBB may not only alter the expression...

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Bibliographic Details
Main Authors: Giulia Sita, Patrizia Hrelia, Andrea Tarozzi, Fabiana Morroni
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2017/7905486