IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection

IL-34 Actions on FOXP3+ Tregs and CD14+ Monocytes Control Human Graft Rejection

Cytokines are major players regulating immune responses toward inflammatory and tolerogenic results. In organ and bone marrow transplantation, new reagents are needed to inhibit tissue destructive mechanisms and eventually induce immune tolerance without overall immunosuppression. IL-34 is a cytokin...

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Bibliographic Details
Main Authors: Séverine Bézie, Antoine Freuchet, Céline Sérazin, Apolline Salama, Nadège Vimond, Ignacio Anegon, Carole Guillonneau
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
IL-34
transplantation
tolerance
monocyte
Treg
cell therapy
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01496/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01496/full

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