Age and life expectancy clocks based on machine learning analysis of mouse frailty

The discovery of interventions that slow aging could be accelerated by employing non-invasive biometrics that predict biological age or life expectancy. Here the authors use longitudinal frailty data from naturally aging mice to develop two such tools, that are responsive to interventions.

Bibliographic Details
Main Authors: Michael B. Schultz, Alice E. Kane, Sarah J. Mitchell, Michael R. MacArthur, Elisa Warner, David S. Vogel, James R. Mitchell, Susan E. Howlett, Michael S. Bonkowski, David A. Sinclair
Format: Article
Language:English
Published: Nature Publishing Group 2020-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18446-0