Paradoxical sleep deprivation increases plasma endothelin levels

The endothelins (ET-1, 2 and 3) constitute a family of 21 amino acid peptides with potent biological activities. ET-1 is one of the most potent endogenous vasoconstrictors so far identified and its increased concentration in plasma appears to be closely related to the pathogenesis of arterial hypert...

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Bibliographic Details
Main Authors: B.D. Palma, A. Gabriel Jr., M. Bignotto, S. Tufik
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2002-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Rat
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000100011