Construction and Functional Characterization of a Fully Human Anti-mesothelin Chimeric Antigen Receptor (CAR) Expressing T Cell
Chimeric antigen receptor (CAR) T cell therapy is considered as an encouraging approach for the treatment of hematological malignancies. However, its efficacy in solid tumors has not been satisfying, mainly in the immunosuppressive network of the tumor microenvironment and paucity of appropriate ta...
Main Authors: | Leila Jafarzadeh, Elham Masoumi, Khadijeh Alishah, Hamid Reza Mirzaei, Arezoo Jamali, Keyvan Fallah-Mehrjardi, Hosein Rostamian, Mohammad Khakpoor-Koosheh, Reza Meshkani, Farshid Noorbakhsh, Jamshid Hadjati |
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Format: | Article |
Language: | English |
Published: |
Tehran University of Medical Sciences
2020-06-01
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Series: | Iranian Journal of Allergy, Asthma and Immunology |
Subjects: | |
Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2670 |
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