New Features about Tau Function and Dysfunction

Tau is a brain microtubule-associated protein that directly binds to a microtubule and dynamically regulates its structure and function. Under pathological conditions, tau self-assembles into filamentous structures that end up forming neurofibrillary tangles. Prominent tau neurofibrillary pathology...

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Bibliographic Details
Main Authors: Miguel Medina, Félix Hernández, Jesús Avila
Format: Article
Language:English
Published: MDPI AG 2016-04-01
Series:Biomolecules
Subjects:
tau
Online Access:http://www.mdpi.com/2218-273X/6/2/21