Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP)

Brain Delivery of a Potent Opioid Receptor Agonist, Biphalin during Ischemic Stroke: Role of Organic Anion Transporting Polypeptide (OATP)

Transporters (expressed) at the blood-brain barrier (BBB) can play an essential role in the treatment of brain injury by transporting neuroprotective substance to the central nervous system. The goal of this study was to understand the role of organic anion transporting polypeptide (OATP1; OATP1A2 i...

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Bibliographic Details
Main Authors: Thamer H Albekairi, Bhuvaneshwar Vaidya, Ronak Patel, Saeideh Nozohouri, Heidi Villalba, Yong Zhang, Yeon Sun Lee, Abraham Al-Ahmad, Thomas J Abbruscato
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceutics
Subjects:
biphalin
organic anion transporting polypeptide
blood-brain barrier
transport mechanism
ischemic stroke
Online Access:https://www.mdpi.com/1999-4923/11/9/467

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https://www.mdpi.com/1999-4923/11/9/467

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