Paroxetine ameliorates prodromal emotional dysfunction and late-onset memory deficit in Alzheimer’s disease mice

Paroxetine ameliorates prodromal emotional dysfunction and late-onset memory deficit in Alzheimer’s disease mice

Abstract Background Neuropsychiatric symptoms (NPS) such as depression, anxiety, apathy, and irritability occur in prodromal phases of clinical Alzheimer’s disease (AD), which might be an increased risk for later developing AD. Here we treated young APP/PS1 AD model mice prophylactically with seroto...

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Bibliographic Details
Main Authors: Peng-Hui Ai, Si Chen, Xian-Dong Liu, Xiao-Na Zhu, Yuan-Bo Pan, Dong-Fu Feng, Shengdi Chen, Nan-Jie Xu, Suya Sun
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Translational Neurodegeneration
Subjects:
Alzheimer’s disease
Paroxetine treatment
Glutamate receptor
Memory deficit
Online Access:http://link.springer.com/article/10.1186/s40035-020-00194-2

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http://link.springer.com/article/10.1186/s40035-020-00194-2

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