Inhibitors of DNA Methyltransferases From Natural Sources: A Computational Perspective

Inhibitors of DNA Methyltransferases From Natural Sources: A Computational Perspective

Naturally occurring small molecules include a large variety of natural products from different sources that have confirmed activity against epigenetic targets. In this work we review chemoinformatic, molecular modeling, and other computational approaches that have been used to uncover natural produc...

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Bibliographic Details
Main Authors: Fernanda I. Saldívar-González, Alejandro Gómez-García, David E. Chávez-Ponce de León, Norberto Sánchez-Cruz, Javier Ruiz-Rios, B. Angélica Pilón-Jiménez, José L. Medina-Franco
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Pharmacology
Subjects:
chemical space
chemoinformatics
databases
DNMT inhibitors
drug discovery
molecular modeling
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01144/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01144/full

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