The GAP activity of type III effector YopE triggers killing of Yersinia in macrophages.

The mammalian immune system has the ability to discriminate between pathogens and innocuous microbes by detecting conserved molecular patterns. In addition to conserved microbial patterns, the mammalian immune system may recognize distinct pathogen-induced processes through a mechanism which is poor...

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Bibliographic Details
Main Authors: Xiaoying Wang, Kaustubh Parashar, Ananya Sitaram, James B Bliska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4148447?pdf=render