DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants

DIXDC1 Phosphorylation and Control of Dendritic Morphology Are Impaired by Rare Genetic Variants

The development of neural connectivity is essential for brain function, and disruption of this process is associated with autism spectrum disorders (ASDs). DIX domain containing 1 (DIXDC1) has previously been implicated in neurodevelopmental disorders, but its role in postnatal brain function remain...

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Bibliographic Details
Main Authors: Vickie Kwan, Durga Praveen Meka, Sean H. White, Claudia L. Hung, Nicholas T. Holzapfel, Susan Walker, Nadeem Murtaza, Brianna K. Unda, Birgit Schwanke, Ryan K.C. Yuen, Kendra Habing, Chloe Milsom, Kristin J. Hope, Ray Truant, Stephen W. Scherer, Froylan Calderon de Anda, Karun K. Singh
Format: Article
Language:English
Published: Elsevier 2016-11-01
Series:Cell Reports
Subjects:
dendrite growth
dendritic spine
autism spectrum disorder
actin
cytoskeleton
neurodevelopment
genetic variants
MARK1
excitatory synapse
Wnt signaling
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471631467X

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http://www.sciencedirect.com/science/article/pii/S221112471631467X

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