Investigation of Endogenous Retrovirus Sequences in the Neighborhood of Genes Up-regulated in a Neuroblastoma Model after Treatment with Hypoxia-Mimetic Cobalt Chloride

Investigation of Endogenous Retrovirus Sequences in the Neighborhood of Genes Up-regulated in a Neuroblastoma Model after Treatment with Hypoxia-Mimetic Cobalt Chloride

Human endogenous retroviruses (ERVs) have been found to be associated with different diseases, e.g., multiple sclerosis (MS). Most human ERVs integrated in our genome are not competent to replicate and these sequences are presumably silent. However, transcription of human ERVs can be reactivated, e....

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Bibliographic Details
Main Authors: Christine Brütting, Harini Narasimhan, Frank Hoffmann, Malte E. Kornhuber, Martin S. Staege, Alexander Emmer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-02-01
Series:Frontiers in Microbiology
Subjects:
endogenous retroviruses
open reading frames
ERVFRD-1
HERV-FRD
human endogenous retrovirus group FRD member 1
hypoxia
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00287/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2018.00287/full

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