Systems Approach to Identify Common Genes and Pathways Associated with Response to Selective Serotonin Reuptake Inhibitors and Major Depression Risk

Systems Approach to Identify Common Genes and Pathways Associated with Response to Selective Serotonin Reuptake Inhibitors and Major Depression Risk

Despite numerous studies on major depressive disorder (MDD) susceptibility, the precise underlying molecular mechanism has not been elucidated which restricts the development of etiology-based disease-modifying drug. Major depressive disorder treatment is still symptomatic and is the leading cause o...

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Bibliographic Details
Main Authors: Ankit Srivastava, Priyanka Singh, Hitesh Gupta, Harpreet Kaur, Neha Kanojia, Debleena Guin, Mamta Sood, Rakesh Kumar Chadda, Jyoti Yadav, Divya Vohora, Luciano Saso, Ritushree Kukreti
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
MDD
SSRI
antidepressant
cushing syndrome
axon guidance
glutamatergic synapse
cAMP signaling pathway
GWAS
Online Access:https://www.mdpi.com/1422-0067/20/8/1993

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https://www.mdpi.com/1422-0067/20/8/1993

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