Dual Role of PTPN22 but Not NLRP3 Inflammasome Polymorphisms in Type 1 Diabetes and Celiac Disease in Children

Dual Role of PTPN22 but Not NLRP3 Inflammasome Polymorphisms in Type 1 Diabetes and Celiac Disease in Children

Genetic polymorphisms in genes coding for inflammasome components nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain-containing protein 3 (NLRP3) and caspase recruitment domain-containing protein 8 (CARD8) have been associated with autoinflammatory and autoimmune diseases...

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Bibliographic Details
Main Authors: Darja Smigoc Schweiger, Katja Goricar, Tinka Hovnik, Andrijana Mendez, Natasa Bratina, Jernej Brecelj, Blanka Vidan-Jeras, Tadej Battelino, Vita Dolzan
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Pediatrics
Subjects:
inflammasome
NLRP3
CARD8
PTPN22
type 1 diabetes
celiac disease
Online Access:https://www.frontiersin.org/article/10.3389/fped.2019.00063/full

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https://www.frontiersin.org/article/10.3389/fped.2019.00063/full

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