Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination

Specific functions of TET1 and TET2 in regulating mesenchymal cell lineage determination

Abstract Background The 5 hydroxymethylation (5hmC) mark and TET DNA dioxygenases play a pivotal role in embryonic stem cell differentiation and animal development. However, very little is known about TET enzymes in lineage determination of human bone marrow-derived mesenchymal stem/stromal cells (B...

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Bibliographic Details
Main Authors: Dimitrios Cakouros, Sarah Hemming, Kahlia Gronthos, Renjing Liu, Andrew Zannettino, Songtao Shi, Stan Gronthos
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Epigenetics & Chromatin
Subjects:
Mesenchymal stem cells
Osteogenesis
Epigenetics
Hydroxymethylation
TET
Osteoporosis
Online Access:http://link.springer.com/article/10.1186/s13072-018-0247-4

Internet

http://link.springer.com/article/10.1186/s13072-018-0247-4

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