Design and synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs as Mycobacterium tuberculosis DNA gyrase inhibitors

Design and synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs as Mycobacterium tuberculosis DNA gyrase inhibitors

Abstract Background Tuberculosis is evidently a major health threat among human populations worldwide. The current study presents the synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs (4a–o) as potential Mycobacterium tuberculosis DNA gyrase inhibitors. DNA gyrase regulates...

Full description

Bibliographic Details
Main Authors: Preeti S. Salve, Prajakta Parchure, Lisel Araujo, Rohini S. Kavalapure, Sunil S. Jalalpure, Dharmarajan Sriram, Vagolu Siva Krishna, Madhu Rekha Estharla, Shankar G. Alegaon
Format: Article
Language:English
Published: SpringerOpen 2021-01-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Mycobacterium tuberculosis
DNA gyrase
Quinoline
Thiazolidin-4-one
Antitubercular activity
Online Access:https://doi.org/10.1186/s43094-020-00162-7

Internet

https://doi.org/10.1186/s43094-020-00162-7

Similar Items