Random Forest Analysis of Untargeted Metabolomics Data Suggests Increased Use of Omega Fatty Acid Oxidation Pathway in Drosophila Melanogaster Larvae Fed a Medium Chain Fatty Acid Rich High-Fat Diet

Obesity is a complex disease, shaped by both genetic and environmental factors such as diet. In this study, we use untargeted metabolomics and Drosophila melanogaster to model how diet and genotype shape the metabolome of obese phenotypes. We used 16 distinct outbred genotypes of Drosophila larvae r...

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Bibliographic Details
Main Authors: Vishal H. Oza, Joseph K. Aicher, Laura K. Reed
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:Metabolites
Subjects:
Online Access:http://www.mdpi.com/2218-1989/9/1/5