Biological and Technical Challenges in Unraveling the Role of N-Glycans in Immune Receptor Regulation

N-glycosylation of membrane receptors is important for a wide variety of cellular processes. In the immune system, loss or alteration of receptor glycosylation can affect pathogen recognition, cell-cell interaction, and activation as well as migration. This is not only due to aberrant folding of the...

Full description

Bibliographic Details
Main Authors: Paola de Haas, Wiljan J. A. J. Hendriks, Dirk J. Lefeber, Alessandra Cambi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00055/full