Enhanced production of recombinant serratiopeptidase in Escherichia coli and its characterization as a potential biosimilar to native biotherapeutic counterpart

Enhanced production of recombinant serratiopeptidase in Escherichia coli and its characterization as a potential biosimilar to native biotherapeutic counterpart

Abstract Background Serratia marcescens, a Gram-negative nosocomial pathogen secretes a 50 kDa multi-domain zinc metalloprotease called serratiopeptidase. Broad substrate specificity of serratiopeptidase makes it suitable for detergent and food processing industries The protein shows potent anti-inf...

Full description

Bibliographic Details
Main Authors: Vishal Srivastava, Shivam Mishra, Tapan K. Chaudhuri
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Microbial Cell Factories
Subjects:
Serratia marcescens
Serratiopeptidase
Escherichia coli
Metalloprotease
Inclusion bodies
Heterologous protein expression
Online Access:https://doi.org/10.1186/s12934-019-1267-x

Internet

https://doi.org/10.1186/s12934-019-1267-x

Similar Items