Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer

Importance of lymph node immune responses in MSI-H/dMMR colorectal cancer

Patients with colorectal cancers (CRCs) generally exhibit improved survival through intensive lymph node (LN) dissection. However, recent progress in cancer immunotherapy revisits the potential importance of regional LNs, where T cells are primed to attack tumor cells. To elucidate the role of regio...

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Bibliographic Details
Main Authors: Koji Inamori, Yosuke Togashi, Shota Fukuoka, Kiwamu Akagi, Kouetsu Ogasawara, Takuma Irie, Daisuke Motooka, Yoichi Kobayashi, Daisuke Sugiyama, Motohiro Kojima, Norihiko Shiiya, Shota Nakamura, Shoichi Maruyama, Yutaka Suzuki, Masaaki Ito, Hiroyoshi Nishikawa
Format: Article
Language:English
Published: American Society for Clinical investigation 2021-05-01
Series:JCI Insight
Subjects:
Oncology
Online Access:https://doi.org/10.1172/jci.insight.137365

Internet

https://doi.org/10.1172/jci.insight.137365

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