Benchmarking algorithms for pathway activity transformation of single-cell RNA-seq data

Biological pathway analysis provides new insights for cell clustering and functional annotation from single-cell RNA sequencing (scRNA-seq) data. Many pathway analysis algorithms have been developed to transform gene-level scRNA-seq data into functional gene sets representing pathways or biological...

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Bibliographic Details
Main Authors: Yaru Zhang, Yunlong Ma, Yukuan Huang, Yan Zhang, Qi Jiang, Meng Zhou, Jianzhong Su
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037020304293