A carboxymethyl dextran-based polymeric conjugate as the antigen carrier for cancer immunotherapy

A carboxymethyl dextran-based polymeric conjugate as the antigen carrier for cancer immunotherapy

Abstract Background Antigen-specific cytotoxic T lymphocytes (CTLs), which eliminate target cells bearing antigenic peptides presented by surface major histocompatibility complex (MHC) class I molecules, play a key role in cancer immunotherapy. However, the majority of tumors are not immunologically...

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Bibliographic Details
Main Authors: Jung Min Shin, Seok Ho Song, N. Vijayakameswara Rao, Eun Sook Lee, Hyewon Ko, Jae Hyung Park
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Biomaterials Research
Subjects:
Carboxymethyl dextran
Cancer immunotherapy
Antigen delivery
Online Access:http://link.springer.com/article/10.1186/s40824-018-0131-0

Internet

http://link.springer.com/article/10.1186/s40824-018-0131-0

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