Eukaryotic initiation factor EIF-3.G augments mRNA translation efficiency to regulate neuronal activity

Eukaryotic initiation factor EIF-3.G augments mRNA translation efficiency to regulate neuronal activity

The translation initiation complex eIF3 imparts specialized functions to regulate protein expression. However, understanding of eIF3 activities in neurons remains limited despite widespread dysregulation of eIF3 subunits in neurological disorders. Here, we report a selective role of the C. elegans R...

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Bibliographic Details
Main Authors: Stephen M Blazie, Seika Takayanagi-Kiya, Katherine A McCulloch, Yishi Jin
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
neuronal excitation
5' utr
translation regulation
seizure
acetylcholine receptor
ncs-2
Online Access:https://elifesciences.org/articles/68336

Internet

https://elifesciences.org/articles/68336

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