Identification of intron 1 and intron 22 inversions of factor VIII gene in Serbian patients with hemophilia A
Hemophilia A (HA) is a common X-linked recessive bleeding disease caused by mutations of FVIII gene. Inversion of intron 1 (inv1) and intron 22 (inv22) are recurrent mutations in severe HA, causing 50% of cases. Inv1 has been reported to occur in 2-5% and inv 22 in 45% of severe HA patients. Our...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Serbian Genetics Society
2013-01-01
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| Series: | Genetika |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0534-0012/2013/0534-00121301207I.pdf |