Clustering and curation of electropherograms: an efficient method for analyzing large cohorts of capillary electrophoresis glycomic profiles for bioprocessing operations

Clustering and curation of electropherograms: an efficient method for analyzing large cohorts of capillary electrophoresis glycomic profiles for bioprocessing operations

The accurate assessment of antibody glycosylation during bioprocessing requires the high-throughput generation of large amounts of glycomics data. This allows bioprocess engineers to identify critical process parameters that control the glycosylation critical quality attributes. The advances made in...

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Bibliographic Details
Main Authors: Ian Walsh, Matthew S. F. Choo, Sim Lyn Chiin, Amelia Mak, Shi Jie Tay, Pauline M. Rudd, Yang Yuansheng, Andre Choo, Ho Ying Swan, Terry Nguyen-Khuong
Format: Article
Language:English
Published: Beilstein-Institut 2020-08-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
capillary electrophoresis
clustering
data analysis
electropherogram
glycosylation
monoclonal antibodies
peak picking
process development
Online Access:https://doi.org/10.3762/bjoc.16.176

Internet

https://doi.org/10.3762/bjoc.16.176

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