Membrane-bound TNF induces protective immune responses to M. bovis BCG infection: regulation of memTNF and TNF receptors comparing two memTNF molecules.

BACKGROUND: Several activities of the transmembrane form of TNF (memTNF) in immune responses to intracellular bacterial infection have been shown to be different from those exerted by soluble TNF. Evidence is based largely on studies in transgenic mice expressing memTNF, but precise cellular mechani...

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Bibliographic Details
Main Authors: Maria L Olleros, Dominique Vesin, Ruth Bisig, Marie-Laure Santiago-Raber, Sonia Schuepbach-Mallepell, George Kollias, Olivier Gaide, Irene Garcia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364241?pdf=render