Polyoma virus-induced osteosarcomas in inbred strains of mice: host determinants of metastasis.

The mouse polyoma virus induces a broad array of solid tumors in mice of many inbred strains. In most strains tumors grow rapidly but fail to metastasize. An exception has been found in the Czech-II/Ei mouse in which bone tumors metastasize regularly to the lung. These tumors resemble human osteosar...

Full description

Bibliographic Details
Main Authors: Palanivel Velupillai, Chang Kyoo Sung, Yu Tian, Jean Dahl, John Carroll, Roderick Bronson, Thomas Benjamin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2809769?pdf=render