Pro-Inflammatory Cytokines Predict Relapse-Free Survival after One Month of Interferon-α but Not Observation in Intermediate Risk Melanoma Patients.

E1697 was a phase III trial of adjuvant interferon (IFN)-α2b for one month (Arm B) versus observation (Arm A) in patients with resected melanoma at intermediate risk. We evaluated the levels of candidate serum cytokines, the HLA genotype, polymorphisms of CTLA4 and FOXP3 genes and the development of...

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Bibliographic Details
Main Authors: Ahmad A Tarhini, Yan Lin, Haris Zahoor, Yongli Shuai, Lisa H Butterfield, Steven Ringquist, Helen Gogas, Cindy Sander, Sandra Lee, Sanjiv S Agarwala, John M Kirwood
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4508028?pdf=render