Extracellular vesicles released by adipose tissue-derived mesenchymal stromal/stem cells from obese pigs fail to repair the injured kidney

Extracellular vesicles released by adipose tissue-derived mesenchymal stromal/stem cells from obese pigs fail to repair the injured kidney

Aims: Mesenchymal stromal/stem cell (MSC)-derived extracellular vesicles (EVs) shuttle select MSC contents and are endowed with an ability to repair ischemic tissues. We hypothesized that exposure to cardiovascular risk factors may alter the microRNA cargo of MSC-derived EVs, blunting their capacity...

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Bibliographic Details
Main Authors: Alfonso Eirin, Christopher M. Ferguson, Xiang-Yang Zhu, Ishran M. Saadiq, Hui Tang, Amir Lerman, Lilach O. Lerman
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:Stem Cell Research
Subjects:
Metabolic syndrome
Renovascular disease
Stem cells
MicroRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120301781

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http://www.sciencedirect.com/science/article/pii/S1873506120301781

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