The Role of Brain-Derived Neurotrophic Factor in Bone Marrow Stromal Cell-Mediated Spinal Cord Repair
The ability of intraspinal bone marrow stromal cell (BMSC) transplants to elicit repair is thought to result from paracrine effects by secreted trophic factors including brain-derived neurotrophic factor (BDNF). Here we used gene therapy to increase or silence BDNF production in BMSCs to investigate...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2015-11-01
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Series: | Cell Transplantation |
Online Access: | https://doi.org/10.3727/096368915X686201 |