The biology and targeting of FLT3 in pediatric leukemia

Despite remarkable improvement in treatment outcomes in pediatric leukemia over the past several decades, the prognosis for high risk groups of acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), as well as for relapsed leukemia, remains poor. Intensified chemotherapy regimens have...

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Bibliographic Details
Main Authors: Colleen eAnnesley, Patrick eBrown
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Oncology
Subjects:
MLL
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2014.00263/full