Crude α-Mangostin Suppresses the Development of Atherosclerotic Lesions in <i>Apoe</i>-Deficient Mice by a Possible M2 Macrophage-Mediated Mechanism

Crude α-Mangostin Suppresses the Development of Atherosclerotic Lesions in <i>Apoe</i>-Deficient Mice by a Possible M2 Macrophage-Mediated Mechanism

Lifestyle choices play a significant role in the etiology of atherosclerosis. Male <i>Apoe</i><sup>&#8722;/&#8722;</sup> mice that develop spontaneous atherosclerotic lesions were fed 0%, 0.3%, and 0.4% mangosteen extracts, composed largely of &#945;-mangostin (MG...

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Bibliographic Details
Main Authors: Masa-Aki Shibata, Mariko Harada-Shiba, Eiko Shibata, Hideki Tosa, Yoshinobu Matoba, Hitomi Hamaoka, Munekazu Iinuma, Yoichi Kondo
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
fatty liver
xanthones
macrophages
M1
M2
therapeutic
<i>Apoe</i> knockout mouse
Online Access:https://www.mdpi.com/1422-0067/20/7/1722

Internet

https://www.mdpi.com/1422-0067/20/7/1722

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