Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells

Long-term survivors of human immunodeficiency virus (HIV) infection have been shown to have a greatly increased incidence of B cell lymphomas. This increased lymphomagenesis suggests some link between HIV infection and the destabilization of the host B cell genome, a phenomenon also suggested by the...

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Bibliographic Details
Main Authors: Xiaohua Wang, Zhi Duan, Guojun Yu, Manxia Fan, Matthew D. Scharff, Anne Moscona
Format: Article
Language:English
Published: American Society for Microbiology 2018-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/9/2/e02315-17