DAF-shielded baculovirus-vectored vaccine enhances protection against malaria sporozoite challenge in mice

DAF-shielded baculovirus-vectored vaccine enhances protection against malaria sporozoite challenge in mice

Abstract Background Previous studies have shown that the baculovirus-vectored vaccine based on the “baculovirus dual expression system (BDES)” is an effective vaccine delivery platform for malaria. However, a point of weakness remaining for use of this vaccine platform in vivo concerns viral inactiv...

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Bibliographic Details
Main Authors: Mitsuhiro Iyori, Daisuke S. Yamamoto, Miako Sakaguchi, Masanori Mizutani, Sota Ogata, Hidesato Nishiura, Takahiko Tamura, Hiroyuki Matsuoka, Shigeto Yoshida
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Malaria Journal
Subjects:
Plasmodium falciparum
Baculovirus
Malaria vaccine
DAF
Transgenic parasites
Online Access:http://link.springer.com/article/10.1186/s12936-017-2039-x

Internet

http://link.springer.com/article/10.1186/s12936-017-2039-x

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