NMR metabolomics of cerebrospinal fluid differentiates inflammatory diseases of the central nervous system.

BACKGROUND:Myriad infectious and noninfectious causes of encephalomyelitis (EM) have similar clinical manifestations, presenting serious challenges to diagnosis and treatment. Metabolomics of cerebrospinal fluid (CSF) was explored as a method of differentiating among neurological diseases causing EM...

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Main Authors: Caitlin D French, Rodney E Willoughby, Amy Pan, Susan J Wong, John F Foley, L Joseph Wheat, Josefina Fernandez, Rafael Encarnacion, Joanne M Ondrush, Naaz Fatteh, Andres Paez, Dan David, Waleed Javaid, Ioana G Amzuta, Anne M Neilan, Gregory K Robbins, Andrew M Brunner, William T Hu, Darya O Mishchuk, Carolyn M Slupsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007045