Integration of miRNA and mRNA expression profiles reveals microRNA-regulated networks during muscle wasting in cardiac cachexia

Abstract Cardiac cachexia (CC) is a common complication of heart failure (HF) associated with muscle wasting and poor patient prognosis. Although different mechanisms have been proposed to explain muscle wasting during CC, its pathogenesis is still not understood. Here, we described an integrative a...

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Bibliographic Details
Main Authors: Leonardo N. Moraes, Geysson J. Fernandez, Ivan J. Vechetti-Júnior, Paula P. Freire, Rodrigo W. A. Souza, Rolando A. R. Villacis, Silvia R. Rogatto, Patricia P. Reis, Maeli Dal-Pai-Silva, Robson F. Carvalho
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-07236-2