Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene.

Genome-wide association scan identifies a risk locus for preeclampsia on 2q14, near the inhibin, beta B gene.

Elucidating the genetic architecture of preeclampsia is a major goal in obstetric medicine. We have performed a genome-wide association study (GWAS) for preeclampsia in unrelated Australian individuals of Caucasian ancestry using the Illumina OmniExpress-12 BeadChip to successfully genotype 648,175...

Full description

Bibliographic Details
Main Authors: Matthew P Johnson, Shaun P Brennecke, Christine E East, Harald H H Göring, Jack W Kent, Thomas D Dyer, Joanne M Said, Linda T Roten, Ann-Charlotte Iversen, Lawrence J Abraham, Seppo Heinonen, Eero Kajantie, Juha Kere, Katja Kivinen, Anneli Pouta, Hannele Laivuori, FINNPEC Study Group, Rigmor Austgulen, John Blangero, Eric K Moses
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3303857?pdf=render

Internet

http://europepmc.org/articles/PMC3303857?pdf=render

Similar Items