Detecting Ethambutol Resistance in Mycobacterium tuberculosis Isolates in China: A Comparison Between Phenotypic Drug Susceptibility Testing Methods and DNA Sequencing of embAB

Detecting Ethambutol Resistance in Mycobacterium tuberculosis Isolates in China: A Comparison Between Phenotypic Drug Susceptibility Testing Methods and DNA Sequencing of embAB

With the increasing incidence of drug-resistant tuberculosis (DR-TB), determining a rapid and accurate drug susceptibility testing (DST) method to identify ethambutol (EMB) resistance in Mycobacterium tuberculosis has become essential for patient management in China. Herein, we evaluated the correla...

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Bibliographic Details
Main Authors: Ma-chao Li, Rong Chen, Shi-qiang Lin, Yao Lu, Hai-can Liu, Gui-lian Li, Zhi-guang Liu, Xiu-qin Zhao, Li-li Zhao, Kang-Lin Wan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Microbiology
Subjects:
Mycobacterium tuberculosis
ethambutol resistance
phenotypic drug susceptibility testing
DNA sequencing
microplate alamarBlue assay
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00781/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2020.00781/full

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