Premature aging in skeletal muscle lacking serum response factor.

Aging is associated with a progressive loss of muscle mass, increased adiposity and fibrosis that leads to sarcopenia. At the molecular level, muscle aging is known to alter the expression of a variety of genes but very little is known about the molecular effectors involved. SRF (Serum Response Fact...

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Bibliographic Details
Main Authors: Charlotte Lahoute, Athanassia Sotiropoulos, Marilyne Favier, Isabelle Guillet-Deniau, Claude Charvet, Arnaud Ferry, Gillian Butler-Browne, Daniel Metzger, David Tuil, Dominique Daegelen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2593784?pdf=render