Prevalence of Prostate Cancer Metastases after Intravenous Inoculation Provides Clues into the Molecular Basis of Dormancy in the Bone Marrow Microenvironment

Prevalence of Prostate Cancer Metastases after Intravenous Inoculation Provides Clues into the Molecular Basis of Dormancy in the Bone Marrow Microenvironment

Bone is the preferred metastasis site of advanced prostate cancer (PCa). Using an in vivo murine model of human PCa cell metastasis to bone, we noted that the majority of animals that develop skeletal metastasis have either spinal lesions or lesions in the bones of the hindlimb. Much less frequentl...

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Bibliographic Details
Main Authors: Younghun Jung, Yusuke Shiozawa, Jingcheng Wang, Natalie McGregor, Jinlu Dai, Serk In Park, Janice E. Berry, Aaron M. Havens, Jeena Joseph, Jin Koo Kim, Lalit Patel, Peter Carmeliet, Stephanie Daignault, Evan T. Keller, Laurie K. McCauley, Kenneth J. Pienta, Russell S. Taichman
Format: Article
Language:English
Published: Elsevier 2012-05-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558612800182

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http://www.sciencedirect.com/science/article/pii/S1476558612800182

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