Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection

Bone Marrow Is a Major Parasite Reservoir in Plasmodium vivax Infection

Plasmodium vivax causes heavy burdens of disease across malarious regions worldwide. Mature P. vivax asexual and transmissive gametocyte stages occur in the blood circulation, and it is often assumed that accumulation/sequestration in tissues is not an important phase in their development. Here, we...

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Bibliographic Details
Main Authors: Nicanor Obaldia, Elamaran Meibalan, Juliana M. Sa, Siyuan Ma, Martha A. Clark, Pedro Mejia, Roberto R. Moraes Barros, William Otero, Marcelo U. Ferreira, James R. Mitchell, Danny A. Milner, Curtis Huttenhower, Dyann F. Wirth, Manoj T. Duraisingh, Thomas E. Wellems, Matthias Marti
Format: Article
Language:English
Published: American Society for Microbiology 2018-05-01
Series:mBio
Subjects:
Aotus
real-time PCR
Saimiri
blood-stage parasites
gametocytes
immunohistochemistry
laboratory animal models
malaria
transcriptome
Online Access:https://doi.org/10.1128/mBio.00625-18

Internet

https://doi.org/10.1128/mBio.00625-18

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