Regulation of motor proteins, axonal transport deficits and adult-onset neurodegenerative diseases
Neurons affected in a wide variety of unrelated adult-onset neurodegenerative diseases (AONDs) typically exhibit a “dying back” pattern of degeneration, which is characterized by early deficits in synaptic function and neuritic pathology long before neuronal cell death. Consistent with this observat...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2017-09-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996117300840 |